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DMT or N, N-dimethyltryptamine in medical talk is a hallucinogenic tryptamine drug. Sometimes referred to as Dimitri, this drug produces effects similar to those of psychedelics, like LSD and magic mushrooms.

Other names for it include:

  • fantasia
  • businessman’s trip
  • businessman’s special
  • 45-minute psychosis
  • spiritual molecule

DMT naturally occurs in many plant species, which have been used in religious ceremonies in some South American countries for centuries. It can also be made in a laboratory.

Ayahuasca is traditionally prepared using two plants called Banisteriopsis caapi and Psychotria viridis. The latter contains DMT while the former contains MAOIs, which prevent certain enzymes in your body from breaking down DMT.

Does it really naturally exist in your brain?

No one knows for sure.

Some experts believe the pineal gland produces it in the brain and releases it when we dream.

Others believe it’s released during birth and death. Some go further to say this release of DMT at death may be responsible for those mystical near-death experiences you sometimes hear about.

What does it feel like?

As with most drugs, DMT can affect people in very different ways. Some truly enjoy the experience. Others find it overwhelming or frightening.

As far as its psychoactive effects, people have described feeling like they’re traveling at warp speed through a tunnel of bright lights and shapes. Others describe having an out-of-body experience and feeling like they’ve changed into something else.

There are also some who report visiting other worlds and communicating with elf-like beings.

Some people also report a pretty rough comedown from DMT that leaves them feeling unsettled.

How is it consumed?

Synthetic DMT usually comes in the form of a white, crystalline powder. It can be smoked in a pipe, vaporized, injected, or snorted.

When used in religious ceremonies, plants and vines are boiled to create a tea-like drink of varying strengths.

How long does it take to work?

Synthetic DMT kicks in pretty fast, producing effects within 5 to 10 minutes.

Plant-based brews tend to produce effects within 20 to 60 minutes.

How long does it last?

The intensity and duration of a DMT trip depends on several things, including:

  • how much you use
  • how you use it
  • whether you’ve eaten
  • whether you’ve taken other drugs

Generally, the effects of inhaled, snorted, or injected DMT last for about 30 to 45 minutes.

Drinking it in a brew like ayahuasca can leave you tripping for anywhere from 2 to 6 hours.

Harm reduction tips

DMT is extremely powerful, even though it naturally occurs in several plant species. If you’re going to try it, there are a few steps you can take to reduce your risk for having a bad reaction.

Keep these tips in mind when using DMT:

  • Strength in numbers. Don’t use DMT alone. Do it in the company of people you trust.
  • Find a buddy. Make sure you have at least one sober person around who can intervene if things take a turn.
  • Consider your surroundings. Be sure to use it in a safe and comfortable place.
  • Take a seat. Sit or lie down to reduce the risk of falling or injury while you’re tripping.
  • Keep it simple. Don’t combine DMT with alcohol or other drugs.
  • Pick the right time. The effects of DMT can be pretty intense. As a result, it’s best to use it when you’re already in a positive state of mind.
  • Know when to skip it. Avoid using DMT if you’re taking antidepressants, have a heart condition, or already have high blood pressure.