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What is Psilocybin (Magic Mushrooms)?

Psilocybin (4-phosphoryloxy-N, N-dimethyltryptamine) and psilocin are chemical compounds obtained from certain types of dried or fresh hallucinogenic mushrooms found in Mexico, South America, and the southern and northwest regions of the United States. Psilocybin is classified as an indole-allylamine (tryptamine). These compounds have a similar structure to lysergic acid diethylamide (LSD) and are abused for their hallucinogenic and euphoric effects to produce a “trip”. Hallucinogenic (psychedelic) effects are probably due to action on central nervous system serotonin (5-HT) receptors. There are over 180 species of mushrooms that contain the chemicals psilocybin or psilocin. Buy Magic Mushroom Online  Denver

Methods of Psilocybin Use

“Magic Mushrooms” have long, slender stems which may appear white or greyish topped by caps with dark gills on the underside. Dried mushrooms are usually a reddish rust-brown color with isolated areas of off-white. Mushrooms are ingested orally and may be made into a tea or mixed into other foods. The mushrooms may be used as a fresh or dried product. Psilocybin has a bitter, unpalatable taste.

A “bad trip”, or an unpleasant or even terrifying experience, may occur with any dose of psilocybin. In general, dried mushrooms contain about 0.2% to 0.4% psilocybin and only trace amounts of psilocin. The typical dose of psilocybin used for recreational purposes varies, with peak effects occurring in 1 to 2 hours, and lasting for about six hours.

Dose and effects can vary considerably depending upon mushroom type, method of preparation, and tolerance of the individual. It can be difficult to determine the exact species of mushroom or how much hallucinogen each mushroom contains. Initial smaller doses and a longer period of time to determine the effects may be a safer option if you choose to use psilocybin for recreational purposes.

Effects of ‘Magic Mushroom’ Use

Psilocybin’s effects are similar to those of other hallucinogens, such as mescaline from peyote or LSD. The psychological reaction to psilocybin use includes visual and auditory hallucinations and an inability to discern fantasy from reality.

 

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Hallucinogens that interfere with the action of the brain chemical serotonin may alter:

mood
sensory perception
sleep
hunger
body temperature
sexual behavior
muscle control

Physical effects of psychedelic mushrooms may include a feeling of nausea, vomiting, muscle weakness, confusion, and a lack of coordination. Combined use with other substances, such as alcohol and marijuana can heighten, or worsen all of these effects.

Other effects of hallucinogenic drugs can include:

intensified feelings and sensory experiences, changes in sense of time (for example, time passing by slowly), increased blood pressure, breathing rate, or body temperature, loss of appetite, dry mouth, sleep problems, mixed senses (such as “seeing” sounds or “hearing” colors), spiritual experiences, feelings of relaxation or detachment from self/environment, uncoordinated movements, lowered inhibition, excessive, sweating, panic, paranoia – extreme and unreasonable distrust of others, psychosis – disordered thinking detached from reality
Larger psilocybin doses, including an overdose, can lead to intense hallucinogenic effects over a longer period of time. An intense “trip” episode may occur, which may involve panic, paranoia, psychosis, frightful visualizations (“bad trip”), and very rarely death. The memory of a “bad trip” can last a lifetime.

How Long Do Mushrooms Stay in Your System?  However, if desired by legal authorities, medical personnel, or an employer, it is possible to perform laboratory assays that can detect any drug or metabolite, including psilocybin, via advanced techniques.

When tested via urine, the psilocybin mushroom metabolite psilocin can stay in your system for up to 3 days. However, metabolic rate, age, weight, age, medical conditions, drug tolerance, other drugs or medications used, and urine pH of each individual may affect actual detection periods.

The extent of Hallucinogenic Mushroom Use

Based on a 2018 survey from SAMHSA’s National Survey on Drug Use and Health (NSDUH), about 5.6 million people aged 12 or older reported using hallucinogens (which may include psilocybin mushrooms) in the year prior to the survey.

In 2018, there were 1.1 million people aged 12 and older who had used hallucinogens for the first time within the past year. In particular, college students, and people ages 18 to 25, may choose mushrooms as a drug of abuse. He’s a very nice guy. He took us out to dinner yesterday, for instance. I enjoy his company because he always tells interesting stories. I pushed the domino. As a result, it fell over.

Are Mushrooms Legal in the U.S.?

However, in November 2020, the state of Oregon passed Measure 109 to legalize psilocybin for people aged 21 and older. Proponents of psilocybin legalization in Oregon promote its use for medical conditions, such as depression, anxiety, or PTSD. The new law will make psilocybin more accessible to people who need them clinically. Measure 109 will be enacted after a developmental stage is completed, expected to be a two-year process. Washington, DC also decriminalized psilocybin in Nov. 2020.

Researchers may only be able to get access to the illegal compound for the study through special waivers from the U.S. Food and Drug Administration (FDA). Other drugs found in federal Schedule I include marijuana, LSD, and heroin.

Medical Uses and Clinical Studies for Psilocybin

Reportedly, cancer can leave patients with this type of psychiatric disorder, feeling that life has no meaning. Typical treatments such as antidepressants may not be effective. However, the use of a single dose of synthetic psilocybin reversed the distress felt by the patients and was a long-term effect. Some advanced cancer patients described the effect of the drug as if “the cloud of doom seemed to lift.”

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